Chronic heart failure causes the cell's powerhouses to malfunction, in part due to overconsumption of an important intermediary compound in energy production. Supplementing the diet to compensate for this could prove a promising strategy for treating heart failure. The findings were published in the journal PNAS by Hokkaido University scientists and colleagues in Japan.
source https://www.lifetechnology.com/blogs/life-technology-science-news/how-heart-failure-disrupts-the-cells-mitochondria