Gut bacteria could be responsible for side effect of Parkinson's drug

Bacteria in the small intestine can deaminate levodopa, the main drug that is used to treat Parkinson's disease. Bacterial processing of the unabsorbed fractions of the drug results in a metabolite that reduces gut motility. These findings were described in the journal BMC Biology on 20 October by scientists from the University of Groningen. Since the disease is already associated with constipation, processing of the drug by gut bacteria may worsen gastrointestinal complications.

Gut bacteria could be responsible for side effect of Parkinson's drug

Bacteria in the small intestine can deaminate levodopa, the main drug that is used to treat Parkinson's disease. Bacterial processing of the unabsorbed fractions of the drug results in a metabolite that reduces gut motility. These findings were described in the journal BMC Biology on 20 October by scientists from the University of Groningen. Since the disease is already associated with constipation, processing of the drug by gut bacteria may worsen gastrointestinal complications.

Significant link found between air pollution and neurological disorders

Air pollution was significantly associated with an increased risk of hospital admissions for several neurological disorders, including Parkinson's disease, Alzheimer's disease, and other dementias, in a long-term study of more than 63 million older U.S. adults, led by researchers at Harvard T.H. Chan School of Public Health.

New evidence to guide the practice of blood transfusions in children with severe malaria

Blood transfusions increase the survival of children admitted to the hospital with complications by severe malaria, and could be beneficial even at higher hemoglobin levels than those currently recommended. These are the main findings of a study led by ISGlobal, a center supported by 'la Caixa' Foundation, and published in The Lancet Haematology.

Vaccine storage demands could leave 3B people in virus cold

From factory to syringe, the world's most promising coronavirus vaccine candidates need nonstop sterile refrigeration to work.

Europe tightens virus curbs as global cases top 40 million

A raft of European nations including Italy and Belgium took desperate new measures on Monday to try to combat a second wave of coronavirus infections as the worldwide caseload topped 40 million.

Unhealthy behaviors trigger same brain responses as bad smells

Unhealthy behaviors trigger moral judgments that are similar to the basic emotions that contribute to our ability to survive. Two hypotheses are prevalent in the current scientific literature as to the identity of these emotions. Some researchers single out disgust, while others opt for pain. After developing a new approach to brain imaging, a research team from the University of Geneva (UNIGE) has come down on the side of disgust. The study, which can be found in Science Advances, shows that unhealthy behaviors trigger brain responses that are similar to those prompted by bad smells. The research also identifies for the first time a biomarker in the brain for disgust.

Haircuts and golf in Melbourne as virus curbs ease

Residents of Australia's second-biggest city flocked to salons and golf courses Monday as some stay-at-home restrictions were eased after coronavirus infection rates fell.

Philips Q3 earnings boosted by virus healthcare demand

Dutch firm Philips said Monday its third quarter net profit rose sharply as its health arm got a boost from demand driven by the coronavirus pandemic.

Children with autism, ADHD have more doctor and hospital visits during infancy

Children who are later diagnosed with autism and/or attention deficit hyperactivity disorder visit doctors and hospitals more often in their first year of life than non-affected children, suggesting a potential new way to identify the conditions early.

Tapping secrets of Aussie spider's unique silk

An international collaboration has provided the first insights into a new type of silk produced by the very unusual Australian basket-web spider, which uses it to build a lobster pot web that protects its eggs and trap prey.

Exercise and nutrition regimen benefits physical, cognitive health

Researchers studied the effects of a 12-week exercise regimen on 148 active-duty Air Force airmen, half of whom also received a twice-daily nutrient beverage that included protein; the omega-3 fatty acid, DHA; lutein; phospholipids; vitamin D; B vitamins and other micronutrients; along with a muscle-promoting compound known as HMB. Both groups improved in physical and cognitive function, with added gains among those who regularly consumed the nutritional beverage, the team reports.

More than 40 million coronavirus cases worldwide

The number of confirmed coronavirus cases worldwide passed 40 million on Monday, according to an AFP tally at 0715 GMT based on official sources.

Alibaba pays $3.6 bn to take over China hypermarket giant SunArt

China's e-commerce behemoth Alibaba has bought a controlling $3.6 billion stake in SunArt which runs hundreds of hypermarkets on the mainland for French shopping giant Auchan.

Can't remember the name of that song? Now you can hum it to Google

Ever had a song stuck in your head that just keeps playing over and over but you can't recall the name or even the words?

Italian PM announces stricter measures to counter virus

Italian Prime Minister Giuseppe Conte on Sunday announced a new series of measures to tackle the rising number of virus cases, with restrictions placed on bars and restaurants and push to increase working from home.

French court tries Russian for multi-million-euro cyberfraud

A Russian goes on trial in Paris Monday accused of having defrauded nearly 200 victims across the world of 135 million euros using ransomware.

As virus flares globally, new strategies target hot spots

After entire nations were shut down during the first surge of the coronavirus earlier this year, some countries and U.S. states are trying more targeted measures as cases Israel and the Czech Republic have reinstated nationwide closures, other governments hope smaller-scale shutdowns can work this time, in conjunction with testing, contact tracing and other initiatives they've now built up.

Canada's Cogeco 'definitively' rejects Altice takeover bid

Canadian telecom giant Cogeco on Sunday definitively rejected an increased takeover bid from Altice U.S., citing the company's "enviable" market position and continued profitability under current ownership.

Irish data regulator probes Instagram: media reports

Ireland's data protection agency is investigating Instagram following concerns over how the image-sharing social platform handled children's personal data, according to media reports.

Big babies could be at higher risk of common heart rhythm disorder in adulthood

Elevated birth weight is linked with developing atrial fibrillation later in life, according to research presented at the 31st Great Wall International Congress of Cardiology (GW-ICC).

Early-arriving endangered Chinook salmon take the brunt of sea lion predation

The Columbia River is home to one of the West Coast's most important Chinook salmon runs. Through late spring and early summer, mature fish return from the sea and begin their arduous journey upriver to spawn. In recent years, these fish have faced an additional challenge: hungry California sea lions.

CBD helps reduce lung damage from COVID by increasing levels of protective peptide

One way CBD appears to reduce the "cytokine storm" that damages the lungs and kills many patients with COVID-19 is by enabling an increase in levels of a natural peptide called apelin, which is known to reduce inflammation and whose levels are dramatically reduced in the face of this storm.

68% of deaths from firearms are from self-harm, majority in older men in rural regions

A new study of gun injuries and deaths in Ontario found that 68% of firearm-related deaths were from self-harm, and they most often occurred in older men living in rural regions, pointing to the need for targeted prevention efforts. The study is published in CMAJ (Canadian Medical Association Journal).

Mystery over decline in sea turtle sightings

The number of sea turtles spotted along the coasts of the UK and Ireland has declined in recent years, researchers say.