Adults with blood cancers respond to booster, not initial dose of COVID-19 vaccine

People with hematologic malignancies—or blood cancers including leukemia, lymphoma, and multiple myeloma—have an impaired immune system due to their disease and its treatment, putting them at risk of severe COVID-19 infection and experiencing a reduced response to COVID-19 vaccination. In a recent study published by Wiley online in Cancer, a peer-reviewed journal of the American Cancer Society, less than half of patients with hematologic malignancies mounted detectable antibodies after initial COVID-19 vaccination, but 56% of "nonresponders" produced antibodies after receiving a booster dose.