Evolutionary 'time travel' reveals enzyme's origins, possible future designs

"The distinction between the past, present and future is only a stubbornly persistent illusion," Albert Einstein wrote. Perhaps this is nowhere more evident than in protein evolution, where past and present versions of the same enzyme exist in different species today, with implications for future enzyme design. Now, researchers have used evolutionary "time travel" to learn how an enzyme evolved over time, from one of Earth's most ancient organisms to modern-day humans.