Aging is a risk factor for the development of osteoarthritis (OA), a chronic disease characterized by degeneration of articular cartilage leading to pain and physical disability. Senescent mesenchymal stem cells (hMSCs) are found in cartilage tissues isolated from patients suffering from osteoarthritis. Notably, senescent MSCs have been regarded as an important therapeutic target for geroprotection against tissue degeneration.
* This article was originally published here
